Argon plasma coagulation (APC) is a medical procedure that applies ionized gas and an electrical current to your digestive tract. It’s performed during a colonoscopy or upper endoscopy to seal bleeding, reduce tumors or stop weight gain after weight loss surgery.
Argon plasma coagulation (APC), also called argon photocoagulation, is a medical procedure performed during a bronchoscopy, colonoscopy or upper endoscopy. Providers use it to treat a variety of conditions in your gastrointestinal system or lungs and airways.
APC uses ionized gas and an electrical current to create blood clots or scars, which can help by stopping internal bleeding or removing growths. It’s a minimally invasive method to access your organs without incisions (cuts).
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Your healthcare provider may recommend APC to:
A gastroenterologist — a physician specializing in the digestive system — usually performs an APC on the digestive tract. A pulmonologist — a physician specializing in the lungs and airway — also may perform the procedure.
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APC is a specific type of ablation therapy. It uses a form of heat to destroy abnormal tissues.
Preparation for argon plasma coagulation depends on whether you have it during:
Your healthcare team may ask you to avoid eating or drinking for several hours before the procedure. Or they may prescribe bowel preparation to clear out your digestive system beforehand. They also may ask you to temporarily stop taking certain medications, like aspirin and blood thinners.
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Your physician may recommend anesthesia to keep you comfortable during APC. This requires inserting a thin tube in your vein (called an intravenous line or IV).
Then, your gastroenterologist will:
Argon plasma coagulation usually takes 15 minutes to an hour.
After the procedure, you’ll stay in a recovery room as you wake up from anesthesia. You may experience some side effects, including:
Your healthcare team will use anesthesia so you don’t feel pain during the procedure.
APC has several potential benefits, including:
APC is generally safe. Complications are rare, but may include:
Most people can return home immediately after APC and resume normal activities the next day. Your doctor may recommend some limitations for a few hours or days, such as:
Complications after APC are rare, but seek medical attention if you experience:
Argon plasma coagulation (APC) is a procedure performed on your digestive tract or lungs and airways. Although APC may sound intimidating, it’s minimally invasive, and your doctor will give you medication to prevent pain. You should be able to go home the same day and resume your usual activities quickly.
Last reviewed on 12/11/2023.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy