Rani second set testing Brolucizumab solution for injection

What is this medication?

BROLUCIZUMAB (broh luh siz yoo mab) treats wet age-related macular degeneration (AMD). It may also be used to treat diabetic macular edema. Brolucizumab reduces growth of new blood vessels in the eye. This medication helps to slow the disease and may help to maintain vision. It is not a cure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): BEOVU

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Eye infection
• Eye inflammation
• Glaucoma
• Recent eye surgery
• An unusual or allergic reaction to brolucizumab, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is injected into the eye. It is given by an ophthalmologist (eye doctor) who specializes in this treatment. It will be given in a hospital or clinic setting.

Talk to your care team regarding the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

What may interact with this medication?

Interactions are not expected. Do not use any other eye products without talking to your care team.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse. Regular eye exams will be needed while you are being treated with this medication.

If you are a woman, use effective birth control during your treatment and for at least 1 month after your last dose.

Tell your care team right away if you have any change in your eyesight. This medication may cause temporary blurred vision. Do not drive or use machinery until your vision has returned to normal.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Bleeding in the front of the eye, including the white, iris or pupil
• Change in vision
• Eye pain
• Heart attack—pain or tightness in the chest, shoulders, arms or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
• New or worsening eye pain, redness, irritation, or discharge
• Sensitivity to light
• Stoke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Blurry vision
• Increased tears after use

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.