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Omidenepag Eye Solution

What is this medication?

OMIDENEPAG (OH mi DEN e pag) treats conditions with increased pressure of the eye, such as glaucoma. It works by decreasing the amount of fluid in the eye, which helps lower eye pressure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): OMLONTI

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Eye injury, infection, or swelling
  • Contact lenses
  • An unusual or allergic reaction to omidenepag isopropyl, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

This medication is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Shake well before using. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or other surfaces. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Do not use your medication more often than directed. Finish the full course of medication prescribed by your care team even if you think your condition is better. Do not stop using except on the advice of your care team.

If you are using another eye product, wait at least 5 minutes between use of this medication and the other eye product.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

Interactions are not expected. Do not use any other eye products without telling your care team.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

Your vision may be tested before and during use of this medication. Tell your care team right away if your eyes get swollen, painful, or have discharge, and see your care team as soon as you can.

This medication may cause your eye, eyelashes, and eyelids to change color. Tell your care team if this happens. If only one eye is being treated with this medication, a difference may develop between the treated and untreated eye in eyelash length, darkness or thickness, and/or color changes of the eyelid skin or iris. These changes may be permanent.

If you wear contact lenses, take them out before putting drops in the eye. Contact lenses may be put back in 15 minutes after putting the drops in your eyes.

Wear dark glasses if this medication makes your eyes more sensitive to light.

If you are going to need eye surgery or other eye procedure, tell your care team that you are using this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Change in vision
  • New or worsening eye pain, redness, irritation, or discharge

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Blurry vision
  • Change in eye, eyelash, or eyelid color
  • Dry eyes
  • Eye irritation or itching
  • Headache
  • Increase in length, thickness, or number of eyelashes
  • Sensitivity to light

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store unopened bottle in the refrigerator. Once opened, store at room temperature between 20 and 30 degrees C (68 and 86 degrees F). Get rid of any unused medication after it expires or 31 days after opening, whichever is first.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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