Iomeprol Injection

What is this medication?

IOMEPROL (EYE oh me prol) helps find or diagnose problems with blood vessels, organs, or other tissues in the body. It works by making parts of the body easier to view during imaging scans, such as CT, MRI, or X-ray. It belongs to a group of medications called contrast agents. The FDA has allowed emergency use of this medication due to shortages of similar products in the U.S. market.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Iomeron 250, Iomeron 300, Iomeron 350, Iomeron 400

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Alcohol use disorder
• Asthma
• Bleeding in the brain
• Brain tumor
• Dehydration
• Diabetes
• Heart disease
• History of blood diseases, such as sickle cell anemia
• Kidney disease
• Myasthenia gravis
• Pheochromocytoma
• Seizures
• Stroke or transient ischemic attack
• Substance use disorder
• Thyroid disease
• An unusual or allergic reaction to iomeprol, iodine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is injected into a vein or artery. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medication is not for regular use.

What may interact with this medication?

• Aldesleukin
• Aspirin and aspirin-like medications
• Certain medications for blood pressure, heart disease, irregular heartbeat
• Certain medications for depression, anxiety, or other mental health conditions
• Cisplatin
• Cyclosporine
• Diuretics
• Medications for infection, such as acyclovir, adefovir, amphotericin B, bacitracin, cidofovir, foscarnet, ganciclovir, gentamicin, pentamidine, vancomycin
• Metformin
• NSAIDs, medications for pain and inflammation, such as ibuprofen or naproxen
• Pamidronate
• Steroid medications such as methylprednisolone and cortisone
• Stimulant medications for ADHD, weight loss, or staying awake
• Zoledronic acid

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
• Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
• High thyroid levels (hyperthyroidism)—fast or irregular heartbeat, weight loss, excessive sweating or sensitivity to heat, tremors or shaking, anxiety, nervousness, irregular menstrual cycle or spotting
• Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
• Low thyroid levels (hypothyroidism)—unusual weakness or fatigue, increased sensitivity to cold, constipation, hair loss, dry skin, weight gain, feelings of depression
• Redness, blistering, peeling, or loosening of the skin, including inside the mouth
• Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Dizziness
• Headache
• Increase in blood pressure
• Nausea
• Pain, redness, or irritation at injection site
• Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.