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Neonatal abstinence syndrome is a condition that affects newborns who receive opioids or addictive substances through the placenta during pregnancy. Babies have withdrawal symptoms during their first few days of life. Treatment is available to help you and your child overcome addiction.
Neonatal abstinence syndrome (NAS) is a condition that affects your newborn when they have exposure to opioid drugs or other addictive substances while in your womb. Your babyreceives these drugs through your placenta, which is an organ that provides oxygen and nutrients from your body to your baby’s body in your uterus.
A newborn could experience neonatal abstinence syndrome (NAS) if their birthing parent took drugs (opioids) or addictive substances during their pregnancy. The most common drugs include:
Additional substances that cause NAS include:
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Neonatal abstinence syndrome affects newborns whose birthing parent took or has an addiction to opioid drugs or addictive substances during pregnancy. Drug addiction is a common condition that affects an estimated 20 million people in the United States.
Neonatal abstinence syndrome (NAS) can be difficult to quantify since the number of cases continues to increase each year. One study suggests there is one newborn diagnosed with NAS every 25 minutes, which equals between 2 to 7 newborns out of every 1,000 births.
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Your newborn will experience withdrawal symptoms until the drug or substance is out of their system. This could create symptoms that cause your child to cry often, be excessively fussy or ill. As a new parent, it could be alarming to see your child in distress. During their withdrawal period, your newborn will be hard to calm. Depending on the severity of your newborn’s symptoms, your child might need to stay in the newborn intensive care unit (NICU) until their body gets rid of the drug or substance that causes their symptoms.
Symptoms of neonatal abstinence syndrome include:
Additional symptoms could include:
Symptoms range in severity for each newborn. The severity of your child’s symptoms vary based on:
If your child has a large number of drugs in their system when they’re born, they could be at risk of having severe, life-threatening symptoms. These symptoms include:
Your baby could experience symptoms of neonatal abstinence syndrome between one to three days after they’re born. Sometimes, it could take up to a week for symptoms to appear. During this time, your newborn will likely stay in your hospital’s newborn intensive care unit (NICU) until the drug leaves their body and they’re healthy enough to go home.
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Long-term symptoms vary depending on the severity of their diagnosis but neonatal abstinence syndrome (NAS) could affect your child as they get older by causing:
Stay up to date with your baby’s wellness checkups to make sure your child reaches developmental milestones according to their age.
Studies suggest that children diagnosed with NAS are more likely to develop the following conditions as they grow:
Drugs or addictive substances that your newborn received through your placenta during pregnancy cause neonatal abstinence syndrome.
Your baby gets oxygen and nutrients from you via their umbilical cord that attaches to your placenta. The placenta is an organ that develops in your uterus during pregnancy. Similar to oxygen and nutrients, drugs that you take can pass through your placenta and reach your baby. Your baby becomes dependent on opioid drugs that they receive in the womb.
If you take opioids before you deliver your baby, your newborn will experience withdrawal symptoms when they’re born until the drug passes through their body.
Since symptoms of neonatal abstinence syndrome (NAS) relate to other conditions for newborns, your provider will diagnose NAS after learning more about your drug intake before your baby was born and by performing a drug screen.
Drug screenings help your provider detect the type and amount of a drug that’s within your newborn’s body. A drug screen takes a sample of the umbilical cord, urine or blood from your newborn. Your provider might also run a meconium test that examines a sample of your newborn’s first bowel movement. You might need to take a drug screening as well to help verify a diagnosis for your baby.
In addition to a drug test, your newborn’s provider will use the NAS scoring system, which is a test where your provider designates points to identify the severity of your baby’s symptoms. The score (results) from this test help your provider offer treatment to alleviate your baby’s symptoms.
Your baby’s treatment for neonatal abstinence syndrome depends on the type of drug and how much of that drug is in their system, as well as their overall health and the severity of their symptoms. Treatment could include:
Treatment typically lasts between five days to six months or until your newborn feels well and doesn’t have any drugs in their body. Treatment to help reduce long-term symptoms could continue throughout your child’s life, which could include cognitive behavioral therapy and medicine to treat conditions that appear as a side effect.
If your newborn has severe symptoms of neonatal abstinence syndrome (NAS), your provider might treat your baby with different types of medicine to alleviate withdrawal symptoms that help them eat and sleep. The goal of prescribed medicine gives your baby small doses of the medicine that is similar to what they received in your womb to wean your baby off of the drug slowly over time instead of letting their body do it all at once (cold turkey), which causes severe symptoms.
Types of medicine to treat NAS includes:
Your newborn may spend several weeks to months in the hospital if they need to take medicine. This helps providers make sure your baby is healthy enough to go home when the drug is out of their body completely.
Your newborn will be fussy and it can be difficult to calm them down while they experience symptoms of withdrawal. You can help your newborn by:
Drugs, like opioids, can pass through your breastmilk (chestmilk) and into your baby’s body if you breastfeed (chestfeed) your newborn. This can cause dangerous side effects for your child. If you’re actively taking drugs that aren’t approved by your healthcare provider, don’t feed your baby your breastmilk. Instead, use formula or donor milk to feed your baby. If you’re in a program and taking a prescribed opioid to prevent you from withdrawal symptoms during or after your delivery, you may give your baby breastmilk if your healthcare providers consider it safe for your baby.
If you have a substance abuse problem or an addiction, talk to your provider about ways to treat your addiction. It’s important to keep yourself healthy so you can be there for your child when they need you most.
You can take steps to prevent severe symptoms of neonatal abstinence syndrome from affecting your baby by:
Your newborn, diagnosed with neonatal abstinence syndrome (NAS), will spend an average of 20 days in the hospital after they’re born to make sure they’re healthy enough to go home. Sometimes treatment for NAS lasts up to six months. Your provider will closely monitor their symptoms to make sure they’re safe and that the drug or substance that is in their system clears before they leave.
Your provider will discuss feeding options on how you can care for your child. If you’re actively taking drugs, don’t breastfeed (chestfeed) your newborn since the drug can pass through your breastmilk, which could cause them to experience symptoms of NAS that affect their health.
When your baby leaves the hospital with you, your newborn will need extra love and support for a few weeks to a few months, as well as through their childhood. Monitor your baby’s growth and development to make sure they don’t miss any milestones. If you notice your child isn’t thriving or misses milestones, talk to your healthcare provider.
Babies born with neonatal abstinence syndrome may experience withdrawal symptoms that last up to six months depending on how much of a drug or substance is in their body. Most babies experience symptoms for an average of 20 days. Your baby will most likely stay in the hospital while they experience symptoms to monitor their health.
If your newborn experiences any symptoms of neonatal abstinence syndrome, visit your healthcare provider. Monitor your child’s development after treatment to make sure they’re on track to meet milestones for their age. If you notice your child misses developmental milestones, contact your provider.
Visit the emergency room or call 911 if your child experiences severe symptoms, especially if your baby:
A note from Cleveland Clinic
Addictions and substance abuse problems can be challenging and overwhelming. These feelings might escalate if you become pregnant and don’t know what to do. Know that treatment is available to help you and your baby live happy and healthy lives. It’s important to be honest with your healthcare provider about the drugs you’re taking during your pregnancy. This is important for your provider to offer treatment unique to you and your situation. It’s always safer to get help than not get any at all.
Last reviewed on 06/12/2022.
Learn more about the Health Library and our editorial process.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
